Tag Archives: crohn’s disease

N-acetylglucosamine for Rebuilding the Gut

When food reactions, medication, or other gut irritants damage the gastrointestinal tract, we need rebuild the gut as well as get rid of these offending agents. Along with improving the diet, replacing good bacteria, and reducing inflammation, I frequently recommend N-acetylglucosamine to aid in gut repair.


N-acetylglucosamine (also known as NAG) is similar to the glucosamine we take for arthritis and joint pain. While NAG might have some of those benefits, it is best know for supporting the body’s creation of a healthy mucus layer in the gut. This normal mucus layer protects our cells from damage by enzymes, acids, bacterial toxins, and more. Additionally, NAG might support the growth of beneficial gut bacterial like Bifidobacterium bifidum. Some interesting studies on multiple sclerosis demonstrate that it may improve immune function as well.

While N-acetylgluosamine might benefit anyone who has substantial digestive issues, it looks particularly promising for people suffering from inflammatory bowel disease. People with conditions like Crohn’s Disease and Ulcerative Colitis tend to have much thinner mucus barriers in the gastrointestinal tract. In a recent study, patients with inflammatory bowel disease taking NAG for 1 month had substantial improvement in their symptoms. Specifically, they had less abdominal pain, diarrhea, and mucus passed in the stool. Even though this wasn’t a placebo-controlled study, the results were impressive enough to make NAG an important consideration for these and related disorders.

Since your digestion is the root of your health, make sure you have a happy GI tract. And stay tuned for more tips on healthier digestion.

P.S. My cat is getting NAG too along with his probiotics.