Fish oil has numerous well-documented benefits for our health. It is probably best known for its cardiovascular advantages of decreasing cholesterol and clotting. Here I am going to focus on its mood supporting qualities, because there have been a number of exciting recent studies. In one study following patients with major depression, the likelihood of also having anxiety was much higher in those with the lowest blood levels of EPA and DHA, the major omega-3 components of fish oil. A second study found that in women a higher intake of omega-3 fatty acids reduced the incidence of elevated depressive symptoms by 49%. This study also pointed out the ratio of omega-3 fatty acids to omega-6 fatty acids was important. This means you can support your mood by both taking fish oil and reducing intake of omega-6 fats like those found in meat and most oils including corn, soy, and vegetable oils.
Fish oil may even be able to reduce suicidal tendencies. It has long been noted in epidemiological studies that low omega-3 levels are correlated with increased rates of suicide. Researchers have also found higher levels of a marker called SAT1 in people with strong suicidal ideation. This marker and related ones were also associated with stress, mood disorders, anxiety, and hallucinations. In mice that were genetically altered to have abnormal expression of these biomarkers, treatment with omega-3 fatty acids brought their levels of the troublesome markers back to normal. All of this very promising research reinforces the use of fish oil as part of the plan to support mental health for even very serious mood disorders.